Apparently, according to Microsoft Support Article 2496653, there is a "known issue" with regards to using a virtual Q: install target while sequencing AutoCAD 2008 with Microsoft App-V 4.6 SP1. The solution is to create a physical partition named Q: to do the sequencing and it will work. I suspect this may apply to other 2008 Autodesk products, as well as other Autodesk products in general. If you use App-V then this may be of interest to consider. If you don't, well, move along - nothing to see here.